careers simera
HOLOGRAPHIC IMAGER CELLNOSTICS PROJECT

PROJECT CONTEXT
• Point-of-care testing
• Health care
• Holography
• Microfluidics
• Medical devices
• Automation

ENGINEERING EXPERTISE PROVIDED
• Optical design and testing
• Electro-optical design and testing
• Mechanical design and development
• Optical calibration
• Automated microfluidic actuation
• Optical diffraction analysis

CHALLENGE

The Council for Scientific and Industrial Research (CSIR) approached Simera to assist them in miniaturizing their prototype point-of-care blood testing device while improving optical quality. Additionally, it was requested to incorporate a system that allows the blood sample to be prepared through microfluidics in an automated fashion.

SOLUTION

Simera started by upgrading the holographic testing rig to make the rig more stable and modular. We then optically modelled the holographic setup in Zemax, correlating measured performance with holographic reconstruction techniques developed by the CSIR. The optical configuration was improved to present a more optimal setup with the inclusion of lenses and a higher performance sensor. In addition, optical performance and correlation with CSIR reverse image construction algorithms were proven. The microfluidic actuation system that creates the blood sample was also improved to be more compact and automated.

OUTCOME

Simera successfully proved that the optimized holographic setup delivered superior results to the previous setup. Through understanding of the design and requested operational features SIMERA identified further improvements for future development. The automated microfluidic system was also successfully proven and maintained repeatability through testing.

HOLOGRAPHIC
HOLOGRAPHIC
CELLNOSTICS